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Frequently Asked Questions

What is the most important information I should know about AURYXIA® (ferric citrate)?

AURYXIA (ah-RICKS-ee-ah) contains iron. Keep it away from children to prevent an accidental ingestion of iron and potentially fatal poisoning. Call a poison control center or your healthcare provider if a child swallows AURYXIA.

 

AURYXIA can increase iron levels in your blood. Iron absorbed from AURYXIA may also increase iron in your body. Your healthcare provider will monitor your iron levels. If you are receiving intravenous (IV) iron, your IV iron dose may be adjusted or discontinued.

What is AURYXIA?

AURYXIA is a prescription medicine that can lower the amount of phosphate in the blood for adult people with chronic kidney disease (CKD) who are on dialysis.

What is hyperphosphatemia (HI-per-FOZ-fa-TEE-mee-uh)?

It’s when your phosphorus levels are too high. When your kidneys are healthy, they remove extra phosphorus from your body. When kidneys fail, phosphorus can build up, causing hyperphosphatemia.

 

It is important to manage your hyperphosphatemia, even if you don’t feel any symptoms.

How does AURYXIA help my hyperphosphatemia?

When you take AURYXIA with meals, the iron in AURYXIA binds (attaches) to the phosphate that was in your food. The bound iron then carries that phosphate to your colon, where it is removed through your bowel movements. This helps to manage your hyperphosphatemia.

Who should not take AURYXIA?

Do not take AURYXIA if you have been diagnosed with an iron overload syndrome, such as hemochromatosis

 

AURYXIA has not been studied in children.

What should I tell my healthcare provider BEFORE taking AURYXIA?

AURYXIA may not be right for you. Before starting AURYXIA, tell your healthcare provider if you:

  • Have any other medical conditions
  • Are pregnant, plan to become pregnant, are breastfeeding or plan to breastfeed

 

Tell your healthcare provider about all of the medicines you take including:

  • The antibiotics doxycycline or ciprofloxacin
  • Prescription and over-the-counter medicines, vitamins, and herbal supplements

 

Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.

What should I tell my healthcare provider AFTER I start taking AURYXIA?
  • Tell your healthcare provider if you have any side effect that bothers you or that does not go away
  • Call your healthcare provider for medical advice about side effects. You may report side effects to Keryx Biopharmaceuticals at 1-844-445-3799 or FDA at 1-800-FDA-1088
  • Let your healthcare provider know if you start a new medication. It may affect your AURYXIA treatment
How should I take AURYXIA?

 

  • Take AURYXIA exactly as prescribed by your healthcare provider
  • Take AURYXIA with meals and adhere to any diet prescribed by your healthcare provider
  • Your healthcare provider will tell you how much AURYXIA to take and may change your dose if necessary
  • Swallow AURYXIA whole. Do not chew or crush
  • If you are taking the antibiotics doxycycline or ciprofloxacin, you will need to take it separately from AURYXIA. Follow your healthcare provider’s instructions on when to take doxycycline or ciprofloxacin while you are also taking AURYXIA
What are possible or reasonably likely side effects of AURYXIA?

The most common side effects of AURYXIA when it is used to lower phosphorus in the blood for adult patients with CKD on dialysis include:

  • Diarrhea
  • Nausea
  • Constipation
  • Vomiting
  • Cough

 

AURYXIA contains iron and may cause dark stools, which is considered normal with oral medications containing iron.

 

These are not all the side effects of AURYXIA. For more information ask your healthcare provider or pharmacist.

 

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

 

Call your healthcare provider for medical advice about side effects. You may report suspected side effects to Keryx Biopharmaceuticals at 1-844-445-3799 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch

How should I store AURYXIA?
  • Store AURYXIA between 68 to 77°F (20 to 25°C)
  • Keep AURYXIA tablets dry