Iron Deficiency Anemia CKD Not On Dialysis

Taking Auryxia Taking Auryxia
Hypothetical patient portrayals.

Here's what you need to know

Keep the information below in mind, but remember to always
take AURYXIA exactly as it was prescribed by your healthcare provider


  • Starting dose:
    1 tablet 3 times a day

  • Maximum dose:
    12 tablets a day

  • Take AURYXIA with meals

  • AURYXIA should only be swallowed and not chewed or crushed


  • Do not take extra medicine to make up the missed dose

  • Take the next dose with your meal, as prescribed

  • Your doctor may adjust the dose to fit your needs.
    Always take AURYXIA as it is prescribed.


  • Doxycycline—Take at least 1 hour before AURYXIA

  • Ciprofloxacin—Take at least 2 hours before or after AURYXIA

  • Be sure to tell your doctor about all the medications you take, including
    over-the-counter medicine, vitamins, and herbal supplements.


  • Dark stools, which is considered normal with oral medications containing iron

  • Diarrhea, which was reported as having no disruption to a moderate disruption
    in normal daily activity in the majority of cases during the clinical trials1-3

  • Nausea, constipation, vomiting, abdominal pain, and cough

  • Talk to your doctor if you are taking other medications that may
    affect these symptoms, such as stool softeners or laxatives.

References: 1. Fishbane S, Block GA, Loram L, et al. Effects of ferric citrate in patients with nondialysis-dependent CKD and iron deficiency anemia. J Am Soc Nephrol. 2017;28(6):1851-1858. 2. Data on File 13, Akebia Therapeutics, Inc. 3. Data on File 27, Akebia Therapeutics, Inc.


Explore how AURYXIA can help


Learn more about your condition

See Important Safety Information below


This information does not take the place of talking to your healthcare provider about your medical condition or treatment

What is the most important information I should know about AURYXIA®(ferric citrate)?

AURYXIA contains iron. Keep it away from children to prevent an accidental ingestion of iron and potentially fatal poisoning. Call a poison control center or your healthcare provider if a child swallows AURYXIA

AURYXIA can increase iron levels in your blood. Iron absorbed from AURYXIA may also increase iron in your body. Your healthcare provider will monitor your iron levels. If you are receiving intravenous (IV) iron, your IV iron dose may be adjusted or discontinued

What is AURYXIA?

AURYXIA is a prescription medicine that can lower the amount of phosphate in the blood for adults with chronic kidney disease (CKD) who ARE on dialysis

For adults who have iron deficiency anemia, as well as CKD, and are NOT on dialysis, AURYXIA is a prescription medicine that can increase hemoglobin levels and increase iron levels in the body

Who should not take AURYXIA?

Do not take AURYXIA if you have been diagnosed with an iron overload syndrome, such as hemochromatosis

AURYXIA may not be right for you. Before starting AURYXIA, tell your healthcare provider if you:

  • have any other medical conditions
  • are pregnant, plan to become pregnant, are breastfeeding or plan to breastfeed

Tell your healthcare provider about all of the medicines you take, including:

  • the antibiotics doxycycline or ciprofloxacin
  • prescription and over-the-counter medicines, vitamins, and herbal supplements

Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine

How should I take AURYXIA?

  • Take AURYXIA exactly as prescribed by your healthcare provider
  • Take AURYXIA with meals and adhere to any diet prescribed by your healthcare provider
  • Your healthcare provider will tell you how much AURYXIA to take and may change your dose if necessary
  • Swallow AURYXIA whole. Do not chew or crush.
  • If you are taking the antibiotics doxycycline or ciprofloxacin, you will need to take it separately from AURYXIA. Follow your healthcare provider's instructions on when to take doxycycline or ciprofloxacin while you are also taking AURYXIA

What are the most common side effects of AURYXIA?

The most common side effects of AURYXIA for use in the treatment of iron deficiency anemia in adult patients with CKD not on dialysis include:

  • diarrhea
  • constipation
  • nausea
  • abdominal pain
  • high levels of potassium in the blood

AURYXIA contains iron and may cause dark stools, which are considered normal with oral medications containing iron

These are not all the side effects of AURYXIA. For more information ask your healthcare provider or pharmacist

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Call your healthcare provider for medical advice about side effects. You may report suspected side effects to Akebia Therapeutics, Inc. at 1-844-445-3799 or FDA at 1-800-FDA-1088 or

How should I store AURYXIA?

  • Store AURYXIA between 68 to 77°F (20 to 25°C)
  • Keep AURYXIA tablets dry

For more information see full Prescribing Information or call 1-844-445-3799